RNA Immunization

RNA immunity is an emerging strategy widely recognized during COVID-19.Inside the body, RNA translates into heterologous proteins, activating T cells and antibody responses.RNA is delivered by lipid nanoparticles (LNP) with inherent immunogenicity, requiring no extra adjuvants.Linear, circular and self-amplifying RNA are widely applied. NBLST offers one-stop solutions for RNA-LNP preparation, RNA immunity and nanobody development, ensuring quality and high efficiency.

RNA Immunization

Technical Principle




Service Highlights




Particle Size Detection

DLS and Cryo-EM data show that the mRNA-LNP prepared by NBLST exhibits excellent particle size uniformity.





Detection of Expression Persistence of Different RNA Types

In vitro luciferase assays demonstrated that circular RNA and self-replicating RNA outperformed conventional linear RNA in both gene expression level and duration.






Case Studies