Antibody Functional Assay Platform

Nanobodies can be utilized in real-time monitoring of receptor activity using the BRET method. According to the information documented in related articles, by constructing corresponding functional plasmids and conducting tests, the obtained results align with those presented in the articles. Leveraging BRET technology, nanobodies enable the real-time assessment of receptor activity.

NBLST StaMimic® platform adopts a proprietary transient transfection technology to achieve uniform gene expression levels within a short timeframe, mimicking the expression profile of stable cell lines. In addition, the platform enables flexible tuning of gene expression intensity. This feature delivers more accurate affinity measurement of antibodies and other binders, as well as more consistent biological phenotypes post gene expression.