E. coli display platform

E. coli display is a prokaryotic surface display system. Antibodies can be displayed on the outer membrane or periplasm for antigen binding. Nanobodies fit this system well due to their simple structure. It has a library capacity up to 1E10. With fast growth and short cycles, it allows upstream affinity enrichment to improve specificity. NabLife’s NabLib® provides E. coli display-based antibody discovery for drug development.

E. coli display platform

Technical principle


Service process


Discovery of Nanobodies



Comparison of Antibody Display Techniques

抗体展示技术比较

 


Service Features 服务特色






Efficient antibody screening

Obtain antibody sequences within 4 weeks

Reduce cloning time

Antibody display / secretion controllable conversion

Enhance sequence specificity

Lower sequence repetition

Increase the success rate of the project

Higher utilization rate of the antibody library




Case Study: Nanobody Screening

SPR