E. coli display platform

E. coli display is a prokaryotic surface display system. Antibodies can be displayed on the outer membrane or periplasm for antigen binding. Nanobodies fit this system well due to their simple structure. It has a library capacity up to 1E10. With fast growth and short cycles, it allows upstream affinity enrichment to improve specificity. NabLife’s NabLib® provides E. coli display-based antibody discovery for drug development.

Technical principle


Service process


Discovery of Nanobodies



Comparison of Antibody Display Techniques

抗体展示技术比较

 


Service Features 服务特色






Efficient antibody screening

Obtain antibody sequences within 4 weeks

Reduce cloning time

Antibody display / secretion controllable conversion

Enhance sequence specificity

Lower sequence repetition

Increase the success rate of the project

Higher utilization rate of the antibody library




Case Study: Nanobody Screening

SPR