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Protein Immunization

Category : Immunization Service • Last Updated : 2025-12-28 11:12:45 • Hits : 64

Multi‑pass transmembrane proteins are key drug targets.NBLST provides proprietary VLP and Nanodisc platforms to prepare high‑quality immunogens and screening antigens in native conformation.

Protein Immunization

Technology Platform


           Traditional VLP production relies on the fluidity of lipid raft structures and packages the host cell membrane during the budding process to form VLPs carrying host membrane proteins.As a result, the inability to display non-lipid-raft-anchored membrane proteins represents an inherent bottleneck of conventional VLP preparation.NBLST has developed an improved VLP production technology that not only increases the total amount of target proteins displayed on VLPs, but also overcomes the limitation of lipid raft dependence.


     



          Nanodisc is an innovative membrane protein purification technology that naturally maintains the native conformation of membrane proteins and preserves their biological functions. It not only facilitates antibody discovery but also provides a revolutionary platform for small‑molecule drug development.NBLST provides highly efficient, stable, and high‑quality Nanodisc products to support the research and development of drugs targeting diverse membrane proteins.



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