Antibody Screening Platform

E. coli display is a prokaryotic surface display system. Antibodies can be displayed on the outer membrane or periplasm for antigen binding. Nanobodies fit this system well due to their simple structure. It has a library capacity up to 1E10. With fast growth and short cycles, it allows upstream affinity enrichment to improve specificity. NabLife’s NabLib® provides E. coli display-based antibody discovery for drug development.

Phage display delivers large libraries and short cycles for antibody screening. Our exclusive plasmid system supports both phage library construction and mammalian expression to boost druggability. NBLST NabLib® offers efficient antibody discovery & engineering via dual-functional phage display to accelerate antibody therapeutics R&D.

NBLST has developed proprietary gene expression technology that precisely restricts the integrated gene copy number per cell to one and tightly regulates the expression level of displayed targets within an appropriate range, preventing compromised screening accuracy caused by overexpression.